Embryonic stem cells have their own strategy for protecting the chromosome ends - search results

. . According to new research by CCR scientists, embryonic stem cells have a unique way of protecting their telomeres, the structures at the ends of chromosomes that shorten with each cell division. A research team led by Eros Lazzerini Denchi, Ph. D.. . , an NIH Stadtman researcher at the CCR Laboratory of Genomic Integrity, found that embryonic stem cells, not like most cells, treat exposed telomeres as damaged DNA, but instead use genes that are normally only used at the earliest stages of development to fight off unwanted DNA repairs. The team's results, derived from studies on mouse embryonic stem cells, will be announced on Jan.. November 2020 published in Nature.