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Associated Press
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Nurse Cath Olmsted, right, gives volunteer Melissa Harting, from Harpersville, IN. s. An injection as the world’s largest study of a potential vaccine for COVID-19, developed by the National Institutes of Health and Moderna Inc.. Starts Monday, 27 July 2020, in Binghamton, IN. s. (AP / Hans Pennink)
For the second time this month, there is promising news from a COVID-19 vaccine candidate: Moderna said Monday that its shots provide robust protection, and a message of hope against the grim backdrop of the soaring coronavirus in the United States.. . s. And around the world.
Moderna said her vaccine appears to be 94. 5% effectiveness according to preliminary data from the company’s ongoing study. A week ago, rival Pfizer Inc did. Announce his COVID-19 vaccine appears to be similarly effective – news that puts both companies on the track to getting permission within weeks for emergency use at U. s.
Dr. Stephen Hogg, President of Moderna, welcomed a « really important milestone » but said it was most reassuring to get similar results from two different companies..
« It should give us all hope that the vaccine will be able to stop this epidemic and hopefully it will bring us back to our lives, » Hogg told the Associated Press.. .
“Moderna will not be alone in solving this problem. He added that it will take many vaccines « to meet global demand. ».
A vaccine cannot come fast enough, with the virus cases topping 11 million in the United States. s. Over the weekend – 1 million of them were registered in just the past week. The epidemic has killed more than one person. 3 million people around the world, more than 245,000 of them in the United States. s.
However, if the FDA permits emergency use of Moderna or Pfizer candidates, there will be limited and fortified supplies before the end of the year.. Both require people to take two injections, several weeks apart. Moderna expects to receive about 20 million doses intended for U. s. By the end of 2020. Pfizer and its German partner BioNTech expect to have received about 50 million doses globally by the end of the year.
The Moderna vaccine, which was created in collaboration with the National Institutes of Health, is being studied on 30,000 volunteers who received the real vaccination or placebo vaccine.. On Sunday, an independent monitoring panel broke the code to check for 95 infections that were recorded starting two weeks after the volunteers’ second dose – and discovered that all but five of the illnesses occurred in the participants who received the placebo.. .
The study is ongoing, and Moderna acknowledges that the rate of protection could change as more COVID-19 infections are discovered and added to the accounts. Also, it is too early to know how long the protection will last. Both warnings apply to the Pfizer vaccine as well.
But our independent moderators reported some additional and promising anecdotes: All 11 severe COVID-19 cases were among those receiving a placebo, and there were no major safety concerns..
The main side effects were fatigue, muscle aches, and injection site pain after the second dose of the vaccine, at rates Hoge described as more common than the flu vaccines but on par with others such as the shingles vaccine.. .
The Cambridge, Massachusetts, vaccine company is among 11 final-stage candidates around the world, four of them in massive studies in the United States. . s.
Both Moderna and Pfizer-BioNTech candidate shots are called mRNA vaccines, and it’s a brand new technology.. It is not made from the Coronavirus itself, which means that there is no chance anyone could catch it from the shots. Instead, the vaccine contains a piece of genetic code that trains the immune system to recognize the spiky protein on the surface of the virus.. .
The powerful results were a surprise. Scientists have warned for months that any injection of COVID-19 may only be as good as flu vaccines, which are 50% effective..
Another acute challenge: dispense doses that have to be kept very cold. Both Moderna and Pfizer shots are frozen but at different temperatures. Moderna announced Monday that once thawed, its doses can last in the refrigerator for longer than initially thought, up to 30 days.. Pfizer shots require long-term storage in extremely cold temperatures.
The Associated Press’s Department of Health and Science is supported by the Howard Hughes Medical Institute’s Division of Science Education. AP is solely responsible for all content.
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