. .
. css-14iz86j-BoldText {font-weight: bold;} rheumatoid arthritis medication tocilizumab appears to treat critically ill people with the Covid-19 virus, early trial data shows.
The drug is no longer under trial because researchers are very confident of the data, but the exact effect on survival is still being calculated.
Tocilizumab targets the immune system, which is spreading in some coronavirus patients. It is this reaction, not the virus itself, that can be fatal.
The trial was conducted by Imperial College London, the United Kingdom’s National Audit and Research Center for Intensive Care and Utrecht University. It focused on the most serious patients, who needed a ventilator.
Trials stopped two days ago as independent observers said there was enough evidence, from the first 303 patients, to show that it worked..
Show improvement in ‘Outcomes’, but this is a statistical confusion of other measures such as survival rates and time in intensive care. Doctors know the drug does something, but it will take time to see if it just saves lives or speeds up recovery..
Professor Anthony Gordon of Imperial said, « We don’t know that yet, and we hope he does both. ».
However, he said it was « very encouraging, » « a great result, » and that tocilizumab could « become the standard of care. ».
It will take weeks to evaluate data that has not yet been officially published.
steroids, . css-yidnqd-InlineLink: url {color: # 3F3F42;}. css-yidnqd-InlineLink: Visited {color: # 696969;}. css-yidnqd-InlineLink: url,. css-yidnqd-InlineLink: visited {font-weight: bolder; border-bottom: 1px solid #BABABA; -webkit-text-decoration: none; text-decoration: none;}. css-yidnqd-InlineLink: link: hover,. css-yidnqd-InlineLink: Visited: hover,. css-yidnqd-InlineLink: link: focus,. css-yidnqd-InlineLink: visited: focus {border-bottom-color: currentcolor; border-bottom-width: 2px; color: # B80000;} @ support (text-underline-offset: 0. 25em) {. css-yidnqd-InlineLink: url,. css-yidnqd-InlineLink: visited {border-bottom: none; -webkit-text-decoration: underline #BABABA; text-decoration: underline #BABABA; -webkit-text-decoration-Thick: 1px; text-decoration-Thick: 1px; -webkit-text-decoration-skip-ink: none; text-decoration-skip-ink: none; text-underline-offset: 0. 25em;). css-yidnqd-InlineLink: link: hover,. css-yidnqd-InlineLink: Visited: hover,. css-yidnqd-InlineLink: link: focus,. css-yidnqd-InlineLink: visited: Focus {-webkit-text-decoration-color: currentcolor; text-decoration-color: currentcolor; -webkit-text-decoration-Thick: 2px; text-decoration-thick: 2px; color: # B80000;}} including dexamethasone, are the only drugs proven to save lives from Covid-19 and tend to calm the entire immune system. Tocilizumab targets specific parts within this complex system.
Dr. Lenny Derdy, Intensive Care Consultant at University Medical Center Utrecht, said: « This is a very impressive result..
“To have an effective second treatment for critically ill patients within months of the start of the epidemic is unprecedented.
However, other experts urged caution until the final results were analyzed, as previous studies gave a mixed picture.
Professor Peter Horby, who was part of the team at Oxford University that showed dexamethasone is protective, said: “This is an encouraging finding that indicates that other more targeted anti-inflammatory drugs may also help.
“Results to date on tocilizumab have been mixed, with four randomized controlled trials reporting results, two of which were negative and two positive.. . . I really look forward to seeing the full results.
It is the first time that a senior US official visiting Israel has made such a trip, which is perceived as controversial..
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Tocilizumab, Arthritis, Roche Holding AG
World News – GB – Tocilizumab: Arthritis Drug May Treat Severe Covid
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Ref: https://www.bbc.co.uk
